Details for gene set INOH_T CELL RECEPTOR SIGNALING (PLC GAMMA, PKC, RAS AND IKK-NF-KAPPAB CASCADE)[GSEA]

Table: GSEA Results Summary

Dataset	Set_04_transDMpreB_versus_DMpreB.phenotype_transDMpreB_versus_DMpreB.cls #transDMpreB_versus_DMpreB.phenotype_transDMpreB_versus_DMpreB.cls #transDMpreB_versus_DMpreB_repos
Phenotype	phenotype_transDMpreB_versus_DMpreB.cls#transDMpreB_versus_DMpreB_repos
Upregulated in class	transDMpreB
GeneSet	INOH_T CELL RECEPTOR SIGNALING (PLC GAMMA, PKC, RAS AND IKK-NF-KAPPAB CASCADE)
Enrichment Score (ES)	0.77350944
Normalized Enrichment Score (NES)	1.722661
Nominal p-value	0.0
FDR q-value	0.10999068
FWER p-Value	0.219

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	ITPR3	9195	31	2.936	0.1403	Yes
2	BTK	24061	118	2.378	0.2507	Yes
3	ITPR1	17341	285	1.959	0.3365	Yes
4	SYK	21636	513	1.619	0.4026	Yes
5	TYK2	12058 19215	563	1.543	0.4746	Yes
6	CSK	8805	940	1.117	0.5084	Yes
7	NFKBIE	23225 1556	1147	0.973	0.5444	Yes
8	NFKBIA	21065	1178	0.947	0.5886	Yes
9	JAK1	15827	1249	0.894	0.6281	Yes
10	RELA	23783	1277	0.876	0.6690	Yes
11	JAK3	9198 4936	1299	0.858	0.7093	Yes
12	TEC	16514	1394	0.805	0.7432	Yes
13	PTK2	22271	1498	0.741	0.7735	Yes
14	PTK2B	21776	2197	0.385	0.7546	No
15	ZAP70	14271 4042	2886	0.219	0.7282	No
16	JAK2	23893 9197 3706	3607	0.130	0.6957	No
17	LAT	17643	3622	0.129	0.7012	No
18	NFKBIB	17906	3771	0.117	0.6989	No
19	PLCG1	14753	5539	0.045	0.6060	No
20	ITK	4934	8021	0.007	0.4729	No
21	PRKCQ	2873 2831	9311	-0.008	0.4040	No
22	SRC	5507	10688	-0.026	0.3312	No
23	CD4	16999	12204	-0.054	0.2524	No
24	NFKB1	15160	13771	-0.113	0.1736	No
25	FYN	3375 3395 20052	15886	-0.398	0.0792	No
26	LCK	15746	17991	-1.398	0.0336	No

Fig 3: INOH_T CELL RECEPTOR SIGNALING (PLC GAMMA, PKC, RAS AND IKK-NF-KAPPAB CASCADE): Random ES distribution
Gene set null distribution of ES for INOH_T CELL RECEPTOR SIGNALING (PLC GAMMA, PKC, RAS AND IKK-NF-KAPPAB CASCADE)